Heavyweights
- Muhammad Ali (PS1)/(N64)
- Frank Bruno (PS1)
- Eric "Butterbean" Esch (PS1)/(N64)
- Jack Dempsey (PS1)
- Joe Frazier (PS1)/(N64)
- Michael Grant (PS1)
- Larry Holmes (PS1)/(N64)
- Evander Holyfield (PS1)/(N64)
- Ingemar Johansson (PS1)
- Lennox Lewis (PS1)/(N64)
- Sonny Liston (PS1)
- Joe Louis (PS1)
- Rocky Marciano (PS1)
- Archie Moore (PS1)
- Ken Norton (PS1)
- Floyd Patterson (PS1)
- Earnie Shavers (PS1)
- Leon Spinks (PS1)/(N64)
- David Tua (PS1)/(N64)
Middleweights
- Oba Carr (PS1)/(N64)
- Julio César Chávez (PS1)
- Héctor Camacho (PS1)
- Oscar De La Hoya (PS1)/(N64)
- Roberto Durán (PS1)/(N64)
- Marvin Hagler (PS1)/(N64)
- Thomas Hearns (PS1)
- Jake Lamotta (PS1)
- Sugar Ray Leonard (PS1)/(N64)
- Bronco McKart (PS1)
- Ike Quartey (PS1)/(N64)
- David Reid (PS1)/(N64)
- Ray Robinson (PS1)
- Fernando Vargas (PS1)/(N64)
- Pernell Whitaker (PS1)/(N64)
Lightweights
- Alexis Argüello (PS1)/(N64)
- Mark Johnson (PS1)
- Kevin Kelley (PS1)/(N64)
- Danny Lopez (PS1)
- Ray Mancini (PS1)
- Angel Manfredy (PS1)/(N64)
- Floyd Mayweather Jr. (PS1)/(N64)
- Barry McGuigan (PS1)
- Erik Morales (PS1)
- Shane Mosely (PS1)/(N64)
- Carlos Navarro (PS1)
- Sean O'Grady (PS1)/(N64)
- Pedro Pena (PS1)
- Aaron Pryor (PS1)/(N64)
- Danny Romero (PS1)/(N64)
Unlockable boxers Celebrity boxers
- Marc Ecko (PS1)
- Jermaine Dupri (PS1)
- Tim Duncan (PS1)
- Marlon Wayans (PS1)
- Qtip (PS1)
- O (PS1)
- Ed Mahone (PS1)
Other boxers
- Mills Lane, a famous referee. (PS1)/(N64)
- Gargoyle, a gargoyle. (PS1)
- Roswell, a alien. (PS1)
- Smacko, a clown. (PS1)